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光叶兔儿风的化学成分研究(PDF)

《广西植物》[ISSN:1000-3142/CN:45-1134/Q]

期数:
2014年03期
页码:
402-407
栏目:
植物化学与化学生物学
出版日期:
2014-07-02

文章信息/Info

Title:
Chemical constituents from Ainsliaea glabra
作者:
陈亚萍12 王书林1 沈云亨2 吴志军3*
1. 成都中医药大学, 成都 611137; 2. 第二军医大学药学院天然药化教研室, 上海 200003; 3. 第二军医大学附属长征医院药学部, 上海 200433
Author(s):
CHEN Ya-Ping12 WANG Shu-Lin1 SHEN Yun-Heng2 WU Zhi-Jun3*
1. Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; 2. Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China; 3. Department of Pharmacology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
关键词:
光叶兔儿风 化学成分 结构鉴定
Keywords:
Ainsliaea glabra chemical constituent structure identification
分类号:
Q946.91
DOI:
-
文献标识码:
A
摘要:
利用正反相硅胶、凝胶(Sephadex LH-20)等多种柱色谱法,对光叶兔儿风化学成分进行分离纯化,并根据理化性质和波谱数据进行结构鉴定。结果表明:已分离得到17个化合物,分别鉴定为蒲公英甾醇乙酸酯(1),三十二碳烯(2),β-谷甾醇(3),大黄酚(4),扇醇棕榈酸酯(5),亚麻酸甲酯(6),亚油酸(7),植物醇(8),[24S]-豆甾-4烯-3-酮(9),植物烯醛(10),白桦脂酸(11),13-羰基-十八碳二烯酸(12),E-7,9-11-羰基-棕榈酸(13),蒲公英酸(14),3β-羟基-胆甾-5-烯(15),环氧树脂烯(16),28-O-月桂酸酯白桦醇(17)。化合物1~17均为首次从该植物中分离得到。
Abstract:
To investigate the chemical constituents of Ainsliaea glabra,several chromatographies including Silica gel column chromatography and Sephadex LH-20 gel column chromatography were applied to the isolation and purification of chemical constituents. The structures were identified on the basis of chemical evidence and spectral data.The results showed that seventeen compounds were isolated from A. glabra and they were identified as taraxasteryl acetate(1),dotriacont-1-ene(2),β-sitosterol(3),chrysophanol(4),lupenyl palmitate(5),methyl linolenate(6),linoleic acid(7),phytol(8),stigmast-4-en-3-one(9),phytenal(10),betulinic acid(11),(9Z,11E)-13-oxo-9,11-ocatadecadienoic acid(12),E-7,9-diene-11-methenyl palmitic acid(13),taraxinic acid(14),3β-hydroxy-cholesta-5-ene(15),epoxylycopaene(16),28-O-laurylbetulin(17). Compounds 1-17 were obtained from this herb for the first time.

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备注/Memo

备注/Memo:
收稿日期: 2013-11-01 修回日期: 2013-12-21
基金项目: 国家重大科技专项项目(2009ZX09502-013)
作者简介: 陈亚萍(1989-),女,浙江兰溪人,硕士在读,主要从事天然产物研究,(E-mail)zlchenyaping@126.com。 *通讯作者: 吴志军,博士,副教授,主要从事中药活性成分及资源评价研究工作,(E-mail)wuzhijun999@sina.com。
更新日期/Last Update: 2014-05-25